Trying to use the Send Email… option in Adobe Reader or Acrobat but you have 64-bit Microsoft Office installed?  After dealing with this issue for many months I finally got tired of it and found a solution.  It involves editing the registry so you have to be careful, but once you are done it will work like you think it should.

Add the following to the registry

[HKEY_LOCAL_MACHINESOFTWAREClientsMailOutlook64Bridge]

“DLLPathEx”=”c:\Windows\winsxs\x86_microsoft-windows-mapi_31bf3856ad364e35_6.1.7600.16385_none_ab2397727b134496\MAPI32.DLL”
“DLLPath”=”c:\Windows\winsxs\x86_microsoft-windows-mapi_31bf3856ad364e35_6.1.7600.16385_none_ab2397727b134496\MAPI32.DLL”

and to set the Default Programs Association

[HKEY_LOCAL_MACHINESOFTWAREClientsMail] @=”Outlook64Bridge”

That should do it.

Here is a screen shot of the registry editor and what it should look like and this is the screen shot of the second part of the changes you need to make